Key Word(s): 1. primary liver cancer; 2. microwave ablation; selleck chemicals llc 3. nursing care; Presenting Author: COSMAS RINALDIA. LESMANA Additional Authors: BILLY ANGGA, LEVINAS. PAKASI, LAURENTIUSA.

LESMANA Corresponding Author: COSMAS RINALDIA. LESMANA Affiliations: Faculty of Medicine, University of Indonesia; Digestive Disease Centre, Medistra Hospital Objective: Autoimmune hepatitis (AIH) is a rare disease which is often late to be diagnosed and may be accompanied by decompensated cirrhosis. Corticosteroid is the mainstay of treatment for patients with autoimmune hepatitis (AIH). However, it is little known whether corticosteroid therapy may produce response in AIH patients with decompensated cirrhosis. This study was aimed to evaluate clinical improvement of AIH patients accompanied with decompensated cirrhosis. Methods: We evaluate a cohort of AIH patients diagnosed between July 2009 and March 2013 in Medistra Hospital, Jakarta. Demographic and laboratory data were retrieved from the patient’s medical record. Diagnosis of AIH was established using serological test or liver biopsy. Patients were treated with low-dose corticosteroid (metil-prednisolone). Data were analysed and presented

descriptively. Results: Twenty-six Buparlisib mouse cases were retrieved during the study period; 18 (69.2%) of them were women. Patients’ mean age was 52.5 + 16.1 years, ranging from 22 to 73 years old. Eleven patients (42.3%) had liver cirrhosis and, six of them had decompensated cirrhosis with ascites and high bilirubin level. These 6 patients received corticosteroid therapy with 8 mg methyl-prednisolone. After treatment, there was a resolution of ascites. Bilirubin were returned to normal from baseline values (15.1 + 10.4 vs. 1.35 + 10.4 mg/dL; p = 0.02). Conclusion: Decompensated cirrhosis in autoimmune hepatitis patients may reflect delayed diagnosis and management. Despite the late stage of disease, decompensated cirrhosis can be improved by conventional corticosteroid therapy. Key Word(s): 1. autoimmune hepatitis; 2. cirrhosis;

3. decompensated; 4. corticosteroid; Presenting Author: SONG YUHU Additional Authors: PAN ZHENGUO, YE 上海皓元医药股份有限公司 JIN, WANG RONG, SHANG HAITAO, XU KESHU, HOU XIAOHUA Corresponding Author: SONG YUHU Affiliations: Union Hospital, Tongji Medical College, Huazhong University of Science and Technology; Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Objective: Primary biliary cirrhosis (PBC) and autoimmune hepatitis (AIH) are immune-mediated liver disorders with the different features. The patients with concomitant features of PBC and AIH have been described as overlap syndrome (OS). There is no consensus on diagnostic criteria of PBC-AIH OS, the aim of the study is to evaluate the performance of three criterion used for diagnosing PBC-AIH overlap syndrome in Chinese patients.