5.0 angstrom/ps, and a region of weak dependence at v > 6.50 angstrom/ps. These investigations may provide some insight into the microcosmic principle of the failure process of polymeric adhesives. (C) 2009 Wiley Periodicals,

Inc. J Appl Polym Sci 115: 460-468, 2010″
“Background Safety and efficacy of fumaric acid esters (FAE) in patients with psoriasis requiring treated comorbidit condition were investigated. Patients and Methods Data collected from 7 dermatology centers were used for a retrospective analysis of patients treated continuously with selleckchem FAE for at least 6 weeks who required at least one medication for a comorbid condition. The records were analyzed at baseline and after 1, 3, 6, 12 and 24 months of therapy. Safety parameters were monitored and the severity

of skin symptoms was assessed by Physician’s Global Assessment’ (PGA). Results A total of 69 patients with moderate to severe psoriasis and a mean duration of 27.4 months of continuous JNK inhibitor treatment were included in the study. In less than 5% were interactions between FAE and co-medications observed. Changes of hepatic, renal or hematological laboratory parameters were usually insignificant and required a modification of FAE treatment in less than 12% of the cases. The percentage of patients documented as markedly improved or clear was 61% after 6 months, 77% after 12 months, and 75% after 24 months of therapy. Conclusions In patients with moderate to severe psoriasis on co-medications, FAE were effective and safe without any noteworthy drug interactions.”
“A CP-690550 cell line systematic study on the energy level alignment, chemical interaction,

and electron doping at interfaces between bathocuproine (BCP) and various types of metals (Au, Cu, Ag, Mg, and Ca) was carried out by performing ultraviolet photoelectron spectroscopy and electronic conductivity measurements. The energy level alignment at BCP/metal interfaces was found to depend on the metal work function (Phi(m)). For BCP on Au and Cu, whose Phi(m) exceeds 4.3 eV, the energy shift in the highest occupied molecular orbital (HOMO) level with respect to the metal Fermi level (E-F) almost accords with the variation in Phi(m). For BCP on Ag, Mg, and Ca, whose Phi(m) is below 4.3 eV, the HOMO energy level is fixed at 3.7 eV with respect to E-F regardless of Phi(m) and new electronic states, called gap states, appeared at BCP/metal interfaces. Since the appearance of gap states is correlated with the energy of the lowest unoccupied molecular orbital (LUMO) level with respect to E-F, these states appear to have formed mainly through the interaction with the LUMO. A clear correlation between the density of the gap states and the vacuum level shift suggesting a charge redistribution at BCP/metal interfaces was found.