Results: Self-reports of cases had substantial concordance with physician selleck records (ICC = 0.74, Cl = 0.61-0.83). As compared to cases, those with problem/very heavy drinking had a significantly higher ICC, and those who were unaffected by alcohol had a significantly lower ICC. However, differences
in concordance disappeared when using regression models that adjusted for factors known to affect the accuracy of self-reported healthcare use. Utilization frequency was a strong predictor of inaccurate reporting.
Conclusions: These findings suggest AUD status may not independently affect the accuracy of self-reports. Counts of physician visits for those with AUD may be considered accurate GSK1838705A when utilization frequency is low. (C) 2010 Elsevier Ireland Ltd. All rights reserved.”
“PURPOSE: To determine whether measurements obtained by partial coherence interferometry (PCI) correlate well with measurements obtained using immersion ultrasound (US) in children.
SETTING: Department of Ophthalmology, Emory
University School of Medicine, Atlanta, Georgia, USA.
DESIGN: Evaluation of a diagnostic test or technology.
METHODS: The charts of pediatric patients who had cataract surgery from August 2008 to September 2009 were reviewed. Axial length (AL) measurements in the operative eye were obtained using PCI at the preoperative clinic visit and then using immersion US in the operating room before surgery. The data were compared to determine the degree of agreement.
RESULTS: The charts of 18 patients (27 eyes) were reviewed. Preoperative AL measurements by PCI were obtained in 21 eyes
(78%). On average, the PCI-measured ALs were 0.1 mm less than the immersion US values (95% confidence interval, -0.2 to -0.1; P = .002). All eyes with an AL of 23.5 mm or less had lower PCI values than immersion US values. There was no systematic pattern of 1 measurement being greater or less than the other in eyes with an AL longer than 23.5 mm.
CONCLUSIONS: There was a systematic difference in AL measurement between PCI and immersion US, with PCI tending to give lower values, particularly in eyes with an AL of 23.5 mm or less. Depending on the length of the eye, a 0.1 mm error in AL measurement GSK2245840 nmr could result in a 0.25 to 0.75 diopter difference in intraocular lens calculation that could be clinically significant in some patients.”
“We investigated a possible association between CASP-10 gene polymorphisms and susceptibility to cancer through a meta-analysis. Eight studies with a total of 29,936 cancer cases and 34,041 healthy controls were included. Meta-analysis results showed that the rs13006529*T carrier was significantly associated with increased cancer risk (OR = 1.17, 95% CI = 1.01-1.36, P = 0.03).