86 +/- 3.95) as compared to oral route (39.60 +/- 6.16). Also it took less time to reach maximum plasma concentration of 21.38 +/- 1.05 ng/ml as compared to oral solution selleck chemical where it required 180 min to reach maximum plasma concentration of 17.98 +/- 1.14. It is concluded from the results that linseed mucilage can be used in the production
of the mucoadhesive microspheres.</.”
“Nanoscale changes to the surface of polymeric materials enables changes in materials’ adhesion, wettability, printability, chemical functionality, and bioactivity, while maintaining desirable bulk properties. Polymer surface modification is therefore used in applications such as antimicrobial or non-fouling materials, biosensors, and active packaging. The range of available modification and analytical techniques used across laboratories prevents accurate comparison of techniques in terms of their effects on surface chemistry and topography. It was therefore our goal to evaluate the effects of four surface modification techniques (chromic acid, piranha solution,
ultraviolet irradiation, and oxygen plasma) on polyethylene films. Changes in surface chemistry and topography were quantified using attenuated total reflectance (ATR) Fourier transform infrared (FTIR) spectroscopy, atomic force microscopy (AFM), contact angle measurement, and direct measurement of available surface carboxylic acids. Roughness increased in the order: piranha (57.7 nm); oxygen plasma (76.3 nm); UV irradiation selleck (76.4 nm); chromic acid (120 nm). Hydrophobicity decreased in the order: piranha (77.20), chromic acid (73.50), oxygen plasma
(61.70), UV irradiation (58.70). Functionalization (by IR absorbance intensity between 1680-1780 cm(-1)) increased in the order: oxygen plasma (0.06), piranha (0.09), chromic acid (0.34), UV irradiation (0.50). By analyzing these methods using consistent analytical techniques, side-by-side comparisons have been accurately made. (C) 2011 Wiley Periodicals, Inc. J Appl Polym Sci 120: 2863-2871, 2011″
“PURPOSE: To assess the repeatability of Tyrosine Kinase Inhibitor Library mw an objective image-analysis technique to determine intraocular lens (IOL) rotation and centration.
SETTING: Six European ophthalmology clinics.
METHODS: Eyes with an Akreos AO aspheric IOL with orientation marks were imaged. A masked observer rated image quality. The axis of rotation was determined from a line bisecting the IOL orientation marks. This was normalized for rotation of the eye between visits using the axis bisecting 2 consistent conjunctival vessels or iris features. The center of ovals overlaid to circumscribe the IOL optic edge and the pupil or limbus were compared to determine IOL centration. Intrasession repeatability was assessed in a subgroup of eyes and the variability of repeated analysis examined.
RESULTS: The SD of intrasession repeatability was +/- 0.79 degrees for IOL rotational stability, +/- 0.