Sufferers of acute COVID-19 infection and those with lingering post-COVID-19 syndrome frequently encounter mental health issues, specifically depression, anxiety, and sleep difficulties. Preliminary evidence from various studies supports the effectiveness of cognitive behavioral therapy, mindfulness-based interventions, acceptance and commitment therapy, and other treatments for this group. While researchers have striven to consolidate the literature on these psychological interventions, previous reviews have been inadequate in the breadth of sources, symptoms, and interventions considered. In addition, most of the investigated studies occurred early in 2020, just as COVID-19's classification as a global pandemic was being established. Significant research has taken place in the years subsequent to that time. Hence, our goal was to provide a refined compilation of the current evidence concerning treatments for the diverse spectrum of mental health symptoms related to COVID-19.
The scoping review protocol's creation was governed by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews. Clinical trial registries (ClinicalTrials.gov), coupled with scientific databases (PubMed, Web of Science, PsycINFO, and Scopus), underwent thorough systematic searches. Studies addressing the efficacy of psychological treatments for acute to post-COVID-19 syndrome were sought within the WHO ICTRP, EU Clinical Trials Register, and Cochrane Central Register of Controlled Trials. this website 17,855 potentially eligible sources/studies, published after January 1, 2020, and with duplicates removed, were identified in a search conducted on October 14, 2022. Six investigators, working independently, will screen titles and abstracts, conduct full-text reviews, and compile data charts. This data will then be summarized using descriptive statistics and narrative synthesis.
This review does not fall under the purview of ethical approval requirements. Conference presentations, academic newspapers, and peer-reviewed journals will serve as avenues for the dissemination of the results. This scoping review's registration with the Open Science Framework is detailed at this URL: https//osf.io/wvr5t.
Ethical review is not a prerequisite for this assessment. A multi-faceted approach to disseminating the results includes peer-reviewed journals, presentations at conferences, and/or articles in academic newspapers. The Open Science Framework (https://osf.io/wvr5t) has archived this scoping review, a detailed investigation of a range of perspectives.

Several essential pillars of the sporting world—sports clubs, healthcare infrastructure, and insurance systems—are heavily burdened by health issues in sport, with the athlete often bearing the greatest weight. The available knowledge base for injury/illness prevention, load management, and stress management for dual-career athletes is not adequately substantiated by rigorous evidence-based research. To determine the effect of physical, psychosocial, and dual-career demands on the occurrence of injuries and illnesses among elite handball players is a key objective of this research approach. Moreover, the aim is to gauge the association between changes in the athletes' workload and the likelihood of injury or illness. This research's secondary objective is to determine the association between objective and subjective stress measurements and to evaluate the potential benefits of certain biomarkers in monitoring stress levels, workload, and the occurrence of injuries or illnesses in athletes.
This prospective cohort study, integral to a PhD project, will observe 200 elite handball players from Slovenia's first men's handball league over the duration of an entire season, from July 2022 until June 2023. Player-level assessments of primary outcomes, encompassing health concerns, loads, and stress, will be conducted weekly. Blood biomarker measurements (cortisol, free testosterone, and Ig-A), along with anthropometric data and life event surveys, will be collected three to five times according to the players' training cycles throughout the observation period.
The National Medical Ethics Committee of Slovenia (number 0120-109/2022/3) approved the project, guaranteeing its execution will conform with the most recent version of the Helsinki Declaration. Dissemination of the research results will include publication in peer-reviewed journals, presentations at various congresses, and the creation of a doctoral thesis. Injury prevention and rehabilitation strategies, and the creation of effective policy recommendations for athlete health, will be greatly enhanced by the implications of these results for the medical and athletic communities.
A return of this data is obligatory for NCT0547129.
The clinical trial NCT0547129.

Despite the demonstrable link between clean water availability and improvements in child health, the health effects of significant water infrastructure upgrades in low-income environments remain underexplored. Annual expenditures of billions of dollars are devoted to upgrading urban water systems, and a rigorous assessment of these upgrades, particularly within informal communities, is indispensable for directing policy and investment plans. To ascertain the effectiveness and impact of water supply improvements, objective measurements of infection, exposure to pathogens, and gut function are paramount.
A study, PAASIM, examines the influence of water system enhancements on the acute and chronic health outcomes of children residing in a low-income urban area of Beira, Mozambique, which comprises 62 sub-neighborhoods and roughly 26,300 households. This matched cohort study, which commenced during late pregnancy, tracked 548 mother-child dyads for a period of 12 months. At the child's 12-month visit, the metrics used to assess primary outcomes include tests for enteric pathogens, assessments of gut microbiome composition, and evaluations of the microbiological qualities of their drinking water source. The supplementary findings encompass the occurrence of diarrhea, the developmental trajectory of children, prior encounters with enteric pathogens, child mortality, and a variety of metrics relating to water access and quality. Our analyses will compare, firstly, subjects residing in sub-neighbourhoods with enhanced water supplies to those inhabiting sub-neighbourhoods lacking such improvements, and secondly, subjects possessing household water connections on their properties to those lacking such connections. this website To optimize investments for improved child health, this research will offer essential data, bridging the knowledge gap on the implications of piped water access for low-income urban populations, using cutting-edge indicators of gastrointestinal illness.
This research undertaking was deemed ethically sound by the Emory University Institutional Review Board and the National Bio-Ethics Committee for Health in Mozambique. The pre-analysis plan is situated on the Open Science Framework platform at the following address: https//osf.io/4rkn6/. Stakeholders will receive the results, locally and through publications.
The Emory University Institutional Review Board and the National Bio-Ethics Committee for Health in Mozambique jointly approved this investigation. The pre-analysis plan, encompassing the study's intended procedure, is published for public viewing on the Open Science Framework (https//osf.io/4rkn6/). The results will be distributed to local stakeholders through publications, and those involved in the process will also receive them.

The improper application of prescription drugs is prompting growing apprehension. Misuse involves the deliberate change of prescribed medication's intended use and/or the employment of illicitly sourced pharmaceuticals, possibly fake or polluted. Of all drugs, prescription opioids, gabapentinoids, benzodiazepines, Z-drugs, and stimulants are those that have the greatest likelihood of being misused.
This research delves into the supply, usage patterns, and health burdens associated with prescription drugs with potential for misuse (PDPM) in Ireland, spanning the years 2010 to 2020. Three correlated studies are planned for execution. Employing national prescription records and law enforcement drug seizures data from national community and prison settings, the initial study will chart the evolution of PDPM supply. A second study is designed to project the progression of PDPM detection, using national forensic toxicology data from diverse early warning systems. The third study, through epidemiological data on drug-poisoning deaths, non-fatal intentional drug overdoses necessitating hospital visits, and drug treatment demand, aims to quantify the national health impact resulting from PDPM.
A retrospective observational study design, using repeated cross-sectional data sets, employed negative binomial regression models or joinpoint regression analysis where appropriate.
The RCSI Ethics Committee (REC202202020) has granted approval for the study. Key stakeholders will receive the findings via research briefs, peer-reviewed publications, and participation in scientific and drug policy meetings.
Approval for the study has been granted by the RCSI Ethics Committee (REC202202020). Key stakeholders will receive the results through research briefs, publications in peer-reviewed journals, and presentations at scientific and drug policy meetings.

Supporting a personalized care system for those with chronic diseases, the ABCC tool has been meticulously developed and validated. this website The rewards of utilizing the ABCC-tool are intrinsically connected to the manner in which it is implemented. This study protocol describes a planned implementation study to clarify when, how, and who uses the ABCC-tool. The study investigates the context, experiences, and implementation process of the ABCC-tool among primary care healthcare providers (HCPs) in the Netherlands.
An implementation study and effectiveness trial are outlined in this protocol, evaluating the ABCC-tool in general practitioner settings. To implement the tool during the trial, written documentation and a video demonstrating the practical application of the ABCC-tool are utilized.