Contrary to our predictions, immunohistochemical and morphometric analyses revealed significantly

greater CIN branching in both newly eclosed and mature major workers, and identified an effect of worker age on branching complexity only in majors. Our results indicate a modulatory role of the CIN in subcaste-specific behaviors and suggest behavioral specialization may be associated with the elaboration of specific MB neurons. (C) 2012 Elsevier Ireland Ltd. All rights reserved.”
“Introduction. Since August 2010, The Brazilian National Transplantation System has allowed performance of liver transplantation (OLT) GM6001 concentration for patients with hepatocellular carcinoma (HCC) beyond the Milan criteria (MC) who have been successfully treated with preoperative downstaging (DS). Herein we sought to compare the clinical profiles Elafibranor and liver explant findings among patients with versus without preoperative DS.\n\nMethodology. Prospective cohort of patients with HCC within and beyond the MC undergoing OLT.

Patients were considered for DS if they were beyond the MC without evidence of vascular invasion or extrahepatic disease. Transcatheter arterial chemoembolization was used for DS, which was considered to be successful if the MC were achieved at any moment during the follow-up.\n\nResults. Between May 2006 and May 2010, we performed 130 OLTs in HCC patients, among whom 10 received preoperative DS. Both groups were comparable for gender, age, P5091 viral etiology, serum levels of alpha fetoprotein, and Child-Pugh and Model for End-Stage Liver Disease (MELD) scores (P > .05). The liver explants were within the MC in 80% of patients with preoperative

DS and 90% of those without preoperative DS. They were comparable for the number of HCC nodules, total tumor size, histologic grade, and presence of microvascular invasion. Patients with pretransplant DS showed larger HCC nodules (33.3 +/- 9.65 vs 26.3 +/- 9.62 mm; P.029) and more frequent macrovascular invasion (1 vs 1 patient, P = .024).\n\nConclusion. Preoperative DS for unresectable HCC may provide a curative treatment for patients who would otherwise be candidates for palliative therapy only. The baseline characteristics and liver explant findings were similar in both groups. We have yet to determine whether the differences observed regarding the size of the largest nodule and the higher frequency of macrovascular invasion have an impact on outcome.”
“OBJECTIVE: To reveal the differences in the parameters of the second order regression curve with a cluster of experimental points on scattergrams showing the dependence of the perimeter on the area of tumor cell nuclei between ductal carcinoma and fibroadenoma of the mammary gland.