‘Declined’ is at least one endoscopist decided NBI is inferior. ‘Unchanged’ is other than above evaluations. Results: Concordance rate of diagnosis by BLI and NBI with microvascular classification was 91.7 %. The preoperative diagnostic rate of depth of invasion was in eight of ten lesions (accuracy rate 80.0%). 50% was improved and 40% was unchanged

in visibility. Only one case was declined by BLI. Conclusion: This study suggested that BLI is equivalent with NBI in the diagnosis of early esophageal cancer. In addition, BLI may have superior visibility compared with NBI. Key Word(s): 1. IEE; 2. BLI; 3. esophageal cancer; Presenting Author: LIANG ZHAO Additional Authors: YI-JUAN DING, HONG-GANG YU, TAO DENG, JUN LIU, HE-SHENG LUO Corresponding Author: LIANG ZHAO Affiliations: Department of Gastroenterology, Renmin Hospital of Wuhan University Objective: To investigate the safety, diagnostic value and clinical impact of double balloon HSP inhibitor PXD101 ic50 enteroscope (DBE) on advanced aged patients and analysis etiological characteristics. Methods: The

clinical data of advanced aged patients underwent DBE in the Department of Gastroenterology in Remin Hospital of Wuhan University from January 2008 to June 2012 were retrospectively analyzed. Results: DBE presents a diagnostic yield of 83.7 %(72/86) and a complication rate of 1.2% (1/86) in 42 advanced aged patients, with clinical impact on 76.2%(32/42) of all patients. The leading causes of OGIB were tumor (53.3%, 11/30) and ulcer (16.7%, 5/30) while angioectasis (6.7%, 2/30) was uncommon. Conclusion: DBE is an G protein-coupled receptor kinase effective and safe method for diagnosis of small bowel disease on advanced aged patients. Tumor and ulcer were common causes of OGIB while angioectasis was uncommon. Diagnosis and therapeutic strategy based on those characteristics is worthy of further investigation. Key Word(s): 1. DBE; 2. Aged patient; 3. Small bowel disease; Presenting Author: SHANYU QIN Additional Authors: HAIXING JIANG Corresponding Author: HAIXING JIANG Affiliations: The First Affiliated Hospital of Guangxi Medical University Objective: Cytological smear is widely employed to analyse specimens

obtained from endosonography-guided fine-needle aspiration (EUS-FNA), but false-negative or inconclusive results may occur. A better diagnostic yield can be obtained from processing cell blocks. We compared the effectiveness of the conventional smear cytology, liquid-based cytology (LBC) and the cell block in the diagnosis of pancreatic neoplasms. Methods: From December 2010 to March 2013, 53 patients with pancreatic tumors were evaluated by EUS-FNA. Surgery was performed in 43 cases, and the other 8 patients were followed clinically for an average of 9 months. In total, all patients were evaluated with cytological smears and cell blocks. The EUS-FNA samples of all patients were processed by conventional smear cytology, liquid-based cytology (LBC) and the cell block. Results: Malignant disease was detected in 39 (73.