SettingDepartment of Orthopedics, the first Hospital affiliated t

SettingDepartment of Orthopedics, the first Hospital affiliated to Zhejiang University of Traditional Chinese Medicine, Hangzhou, China.

SubjectsNinety patients with degenerative osteoarthritis undergoing TKA.

InterventionsThe AA group RSL3 Metabolism inhibitor received true AA by embedding vaccaria seeds at four specific AA points (knee joint, shenmen, subcortex, sympathesis) ipsilateral to the surgery site, while the control group received

four nonacupuncture points on the auricular helix.

Outcome MeasuresVisual analog scale (VAS), the consumption of analgesic via patient-controlled analgesia, the incidence of analgesia-related adverse effects, Hospital for Special Surgery scores (HSS), and range of motion (ROM) were recorded.

ResultsVAS scores were similar at 12, 24, 36, and 48h postsurgery (P>0.05), but AA group scores were lower than those of the control group at 3, Saracatinib chemical structure 4, 5, and 7 days (P<0.05). Patients in the AA group

consumed lower doses of analgesic than those in the control group after surgery (P<0.05). The incidence of analgesia-related adverse effects in the AA group was lower than that in the control group (P<0.05). Although HSS scores were similar in the two groups preoperatively and at 3 months postoperatively (P>0.05), HSS scores 2 weeks postoperatively were higher in the AA group than in the control group (P<0.05), but there was no difference between groups in ROM (P>0.05).

ConclusionsApplying auricular acupoint acupressure in the perioperative period of TKA is favorable for alleviating postoperative pain, decreasing opioid consumption and its adverse effects, and promoting early rehabilitation. Also, this intervention has the advantage of lower costs, fewer complications, simple application, and high safety.”
“The primary purpose was to test the effectiveness of two telephone-delivered psychosocial interventions for maintaining and improving quality of life (QOL) (psychological, physical, social,

and spiritual well-being) among 71 prostate cancer survivors and the 70 intimate or family partners who were supporting them in their recovery.

This study used a three-wave repeated measures experimental design. Both the LY2606368 interpersonal counseling intervention (TIP-C) and health education attention condition (HEAC) were delivered using the telephone.

Improvements in depression, negative affect, stress, fatigue, and spiritual well-being were significantly higher for survivors in the HEAC than for those in the TIP-C condition. Partners in the HEAC condition showed significantly greater improvements in depression, fatigue, social support from family members, social well-being, and spiritual well-being compared to partners in the TIP-C condition. The results revealed superior outcomes for those assigned to the HEAC intervention.

The psychosocial interventions in this study were effective in maintaining or improving the QOL for prostate cancer survivors and their partners.

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