“
“The different natural oils epoxidized with 3-chloroperbenzoic
acid were crosslinked with diepoxy reactive diluents, bisphenol A propoxylate diglycidyl ether, and 3,4-epoxycyclohexylmethyl-3,4-epoxyclohexane-carboxylate, using AG-881 Metabolism inhibitor cationic initiator at 60 degrees C and photoinitiators at the room temperature. The insoluble fraction of the polymeric products was 59-90%. The Young modulus of the crosslinked polymer films ranged from 2 to 861 MPa. The 10% weight loss temperatures of the crosslinked polymers estimated by thermogravimetric analysis were in the range from 250 to 420 degrees C. The water vapor transmission rate of the crosslinked biopolymer films ranged from 6 to 49 g/m(2)/24 h. Biochemical oxygen demand and biodegradation in soil of the crosslinked polymers were studied. The crosslinked polymers showed higher biodegradation rate than cellulose, starch, and polyvinylalcohol. (C) 2009 Wiley Periodicals, Inc. J Appl Polym Sci 115: 2028-2038, 2010″
“This noninterventional single-arm study explored effectiveness and behavioral outcomes in intellectually disabled patients treated with topiramate for epilepsy. Data from 21 patients diagnosed with cerebral palsy were available for evaluation.
Behavioral changes were assessed using the validated Aberrant Behavior Checklist and Matson Evaluation of Social Skills for individuals with Severe Retardation (MESSIER) scales. Some improvement CX-6258 supplier in nearly all behavioral aspects was observed under concomitant topiramate therapy; for example, the Aberrant Behavior Checklist total score changed from 33.7 +/- 25.8 to 25.3 +/- 19.1
(P = 0.047). In addition, seizure frequency decreased from 16.1 +/- 22.2/4 weeks to 12.2 +/- 17.0/4 weeks (N = 2 1, P = 0.164). Fifty-two percent of the patients experienced at least 50% seizure reduction during the 24-week treatment period. The safety profile is in accordance with the current Summary of Product Characteristics of Topiramate. Two unexpected deaths were attributed to sudden unexpected death in epilepsy. (C) 2009 Elsevier Inc. All rights reserved.”
“Study Design. Prospective, controlled, observational outcome study using clinical, radiographic, and patient/physician-based questionnaire data, with patient outcomes at 12 months selleck chemicals follow-up.
Objective. To validate appropriateness criteria for low back surgery.
Summary of Background Data. Most surgical treatment failures are attributed to poor patient selection, but no widely accepted consensus exists on detailed indications for appropriate surgery.
Methods. Appropriateness criteria for low back surgery have been developed by a multispecialty panel using the RAND appropriateness method. Based on panel criteria, a prospective study compared outcomes of patients appropriately and inappropriately treated at a single institution with 12 months follow-up assessment. Included were patients with low back pain and/or sciatica referred to the neurosurgical department.