Analysis of respondents’ drinking patterns revealed that 40.9% did not use any alcohol during the follow-up period and that 5.5% had seldom used alcohol. The inhibitor Veliparib latter two groups can be considered as the ‘non-relapse’ group (46.4%) or the number of successful outcomes. Another 12.2% regularly used alcohol but in a controlled way, while 8.8% occasionally abused Inhibitors,Modulators,Libraries alcohol. On the other hand, excessive alcohol use occurred periodically among 8.8% of the respondents, while nearly a quarter (23.8%) used excessively during almost the entire follow-up period. Given these high relapse rates, it may not surprise that nearly one third of the respondents (32.6%) had been readmitted to residential treatment during the follow-up period, while 17.1% had followed outpatient treatment for their alcohol problems.

Table 1 Comparison of the number of days and severity of substance use and psychological problems at baseline and 6 months after the residential treatment episode (n = 181) According to respondents’ personal estimation, half of them (53.9%) did not experience any problems with alcohol during the 30 days Inhibitors,Modulators,Libraries preceding the follow-up interview, while 16.7% stated they experi-enced such problems almost daily. Similarly, 53.3% felt not bothered at all by their alcohol problems, but the vast majority (76.1%) said they still needed help to further overcome their alcohol problems. Psychological health The severity of psychological problems was obviously lower at the time of follow-up (Table (Table1),1), which was further illustrated by the fact that significantly (according to the Wilcoxon matched pairs test) fewer respondents experienced depressive symptoms (T-=56, T+=17; Z=-4.

565; Inhibitors,Modulators,Libraries p = 0.000), feelings of anxiety/tension (T-=63, T+=25; Z=-4.051; p = 0.000) or problems with aggression control (T-=26, T+=9; Z=-2.874; p = 0.004). Inhibitors,Modulators,Libraries Moreover, less persons were Inhibitors,Modulators,Libraries prescribed medication for psychological problems (T-=42, T+=9; Z=-2.794; p = 0.005), had suicidal thoughts (T-=42, T+=20; Z=-3.938; p = 0.000) or attempted to commit suicide (T-=37, T+=10; Z=-2.111; p = 0.035). In addition, the number of days that respondents experienced psychological problems reduced significantly (Table (Table1).1). Also, significantly fewer persons felt bothered by or needed help for psychological problems, but 30.3% had an ASI-severity score ��4 for psychological problems, indicating that some kind of treatment was still recommended.

Since the end of the residential treatment episode, 25.1% of the respondents had followed outpatient treatment and 17.3% had been treated residentially for psychological problems. Entinostat Half of all respondents (52%) expressed they had experienced at least some days of psychological problems during the past 30 days, mainly feelings of anxiety/tension (42.5%), depressive feelings (39.7%) and suicidal thoughts (12.8%). 27.9% had been prescribed medication for these psychological problems.